DMAE or Syn-Ake

There has been some talk on skincare boards about sagging skin or skin getting more crepey as we age. Yes, it does. It isn’t a fun thing but it does happen. A number of people have been suggesting DMAE also known as Dimethylaminoethanol, dimethylethanolamine, or Deanol. They do have good reason to suggest this ingredient. However, there is also Syn®-Ake.

DMAE studies

There are studies on DMAE to back up the claim that it does firm the skin. This study indicated that at a lower percentage rate DMAE did have some anti-aging effects on the skin without damaging side effects. Other studies have indicated the same all in fairly low percentages. I am still looking for more studies with this ingredient that combines antioxidants or other active ingredients. So far I haven’t found any of these studies.

In real life, quite of few people on these boards have stated they have seen some great results with this ingredient.

DMAE in beauty products

How do you find it in beauty products? Some you have to look at labels, but two brands stand out with having this ingredient in a number of their products.

Perricone MD and Derma E

I choose to feature these two because I have had some experience with both brands. Perricone MD is a brand known for completing a number of studies on their ingredients, even some that are double-blind studies. So I can appreciate their products for the research and quality they put into their products.

Derma E is a company that I purchase from my local health food store. They may not have the funds to do the big studies but their products seem to be clean and use ingredients that have some research behind them as well.

Syn®-Ake or Dipeptide Diaminobutyroyl Benzylamide Diacetate

There is another ingredient which is a neuropeptide (tripeptide-3). It works much in the same way as DMAE. It is Syn®-Ake or Dipeptide Diaminobutyroyl Benzylamide Diacetate. I find this ingredient so interesting because it is a protein fragment from the venom of a snake. It sounds scary, doesn’t it? “I am going to put that on my face?” Yep, because it smooths and tightens the skin.

Syn®-Ake or Dipeptide Diaminobutyroyl Benzylamide Diacetate is a very small molecule so it penetrates the skin barrier easily. It signals the muscles to relax, yet communicates with the cells in the upper level to tighten.

The Study

This ingredient also has a study. There are more studies than just this one, but I liked this study best because it has pictures. Isn’t it so funny how seeing is believing? In a study, everything is controlled so I can rely a bit more on the pictures contained in a study.

In beauty products

You may already be familiar with this ingredient and not even know it. Peter Thomas Roth has had this ingredient in a number of his products for years now. In fact, Peter Thomas Roth products are what got me hooked on skincare about 15 years ago and I still love this brand.

Currently, it is in my routine in The Ordinary Buffet + Copper Peptides. It is also in The Ordinary Buffet. I am always amazed at what a great value these two products are in skincare. One is around $30.00 for 1oz and the other is around $30.00 for 2oz. The difference is copper. I would go for the copper. I have a post on the benefits of copper (along with studies).

In the study above on the neuropeptide (Dipeptide Diaminobutyroyl Benzylamide Diacetate or Syn®-Ake. It was used alongside antioxidants. Antioxidants are so important in our skincare routine. If you use nothing else use an antioxidant. (I would prefer you to use more, but if that is all you can do. There are antioxidants in some lotions along with SPF.)

Firming products

If you are wondering exactly what these ingredients are supposed to firm, it would be the jawline. The forehead and the 11s (the area between you two eyebrows), that is what most people find to be the most beneficial areas. In the studies, there are also effects on your crows’ feet. I am sure the lower neck wouldn’t be any different and you would see effects on that part as well. You have to keep in mind that it takes time. It took time to get here, it takes time to get back.

You also have to keep in mind that it isn’t one ingredient along that works on the skin. It is a combination. Just like your body doesn’t work on one protein, vitamin or enzyme. That is over simplified, but you understand.

DMAE or Syn®-Ake

A firming ingredient is very important in a mature skin routine. It is up to you if you want to use DMAE or Syn®-Ake or a form thereof in your routine. You do have a choice. There are both studied ingredients so check out the studies and come to your own conclusion.

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